S100B antibody (AA 2-92) (Biotin)

Catalog No. ABIN7166084

This Rabbit Polyclonal antibody specifically detects S100B in ELISA. It exhibits reactivity toward Human.

Quick Overview for S100B antibody (AA 2-92) (Biotin) (ABIN7166084)

Target: S100B (S100 Calcium Binding Protein B (S100B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This S100B antibody is conjugated to Biotin

Application: ELISA

Product Details anti-S100B Antibody (Biotin)

Binding Specificity: AA 2-92

Purpose: S100B Antibody, Biotin conjugated

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Protein S100-B protein (2-92AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for S100B

Target: S100B (S100 Calcium Binding Protein B (S100B))

Alternative Name: S100B

Background:

Background: Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

Aliases: NEF antibody, Protein S100 B antibody, Protein S100-B antibody, S 100 calcium binding protein beta chain antibody, S 100 protein beta chain antibody, S-100 protein beta chain antibody, S-100 protein subunit beta antibody, S100 antibody, S100 calcium binding protein beta (neural) antibody, S100 calcium-binding protein B antibody, S100 protein beta chain antibody, S100B antibody, S100B_HUMAN antibody, S100beta antibody

UniProt: P04271

Pathways: Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins